产品货号：
Z31992
中文名称：
CDC6抗体
英文名称：
Anti-CDC6 Antibody (Clone#DCS-180)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CDC6 Antibody (Clone#DCS-180) |
| 指标别名 | Cdc18 related protein;CDC18L;CDC6;CDC6 related protein;HsCDC18;HsCDC6;p62(cdc6) |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | CDC6 |
| 克隆号 | DCS-180 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Recombinant human Cdc6. |
| 实际分子量 | 63KD |
| 成分 | 200μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Ascites |
| 浓度 | 200μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | In yeasts,Cdc6(Saccharomyces cerevisiae) and Cdc18(Schizosaccharomyces pombe) associate with the origin recognition complex(ORC) proteins to render cells competent for DNA replication.Cdc6 is overexpressed in human cancers,where it has a critical regulatory role in addition to DNA replication.Yan et al.(1998) showed that Cdc6 is expressed selectively in proliferating but not quiescent mammalian cells,both in culture and within tissues in intact animals.During the transition from a growth-arrested to a proliferative state,transcription of mammalian Cdc6 is regulated by E2F proteins,as revealed by a functional analysis of the human Cdc6 promoter and by the ability of exogenously expressed E2F proteins to stimulate the endogenous Cdc6 gene.They conclude that expression of human Cdc6 is regulated in response to mitogenic signals though transcriptional control mechanisms involving E2F proteins,and that Cdc6 is required for initiation of DNA replication in mammalian cells. |
| Uniprot ID | Q99741 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | cell division cycle 6 homolog(S.cerevisiae) |
| 蛋白名全称 | Cell division control protein 6 homolog |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：CDC6抗体，CDC6单抗，Anti-CDC6 Antibody (Clone#DCS-180)